Authors

  1. Vuletic, S. MD
  2. Bell, K. R. MD
  3. Jain, S. PhD
  4. Bush, N. PhD
  5. Temkin, N. PhD
  6. Fann, J. R. MD, MPH
  7. Stanfill, K. E. PhD
  8. Dikmen, S. PhD
  9. Brockway, J. A. PhD
  10. He, F. MS
  11. Ernstrom, K. MS
  12. Raman, R. PhD
  13. Grant, G. MD, FACS
  14. Stein, M. B. MD, MPH
  15. Gahm, G. A. PhD
  16. for the CONTACT Investigators

Abstract

Objective: Evaluate sleep quality, its correlates, and the effect of telephone-based problem-solving treatment (PST) in active duty postdeployment service members with mild traumatic brain injury (mTBI)

 

Setting: Randomized clinical trial.

 

Participants: Active duty service members with combat-related mTBI.

 

Study design: Education-only (EO) and PST groups (N = 178 each) received printed study materials and 12 educational brochures. The PST group additionally received up to 12 PST telephone calls addressing participant-selected issues. Outcomes were evaluated postintervention (6 months) and at 12 months.

 

Main Measure: Pittsburgh Sleep Quality Index.

 

Results: Sleep quality was manifestly poor in both groups at baseline (Pittsburgh Sleep Quality Index = 12.5 +/- 4). Overall sleep quality was significantly different between the PST and EO groups at 6 months (P = .003) but not at 12 months. Longitudinally, PST significantly improved sleep quality at 6 months (P = .001) but not over the follow-up. Low sleep quality was associated with concussion symptoms, pain, depression, and posttraumatic stress disorder at all time points (P < .0001).

 

Conclusions: Sleep disorders, common in postdeployment service members with mTBI, are strongly associated with the presence of pain, posttraumatic stress disorder, and depression. Telephone-based PST may be an effective therapeutic approach for reducing sleep disorders in this population. Research should focus on maintenance of treatment gains.