Study finds use of aspirin is also associated with a lower risk of distant recurrence
WEDNESDAY, Feb. 17 (HealthDay News) -- Women with breast cancer who take aspirin several days a week have a lower risk of death or recurrence, according to a study published online Feb. 15 in the Journal of Clinical Oncology.
Michelle D. Holmes, M.D., of Brigham and Women's Hospital in Boston, and colleagues examined the association between self-reported aspirin use and mortality among 4,164 female registered nurses with breast cancer.
The researchers recorded 341 deaths from breast cancer. More frequent, current aspirin use was associated with a significantly lower risk of death, with an adjusted relative risk of 1.07 for use once a week and an adjusted relative risk of 0.36 for use six to seven days per week. The association was not significantly affected by stage, menopausal status, body mass index, or estrogen receptor status. Similar results were observed for distant recurrence, with an adjusted relative risk of 0.91 for aspirin use once a week and an adjusted relative risk of 0.40 for use six to seven days per week.
"Among women living at least one year after a breast cancer diagnosis, aspirin use was associated with a decreased risk of distant recurrence and breast cancer death," the authors conclude.