Metabolic Syndrome Linked to Overactive Bladder in Females

Metabolic syndrome diagnosed in significantly more patients with overactive bladder than controls

THURSDAY, Dec. 29 (HealthDay News) -- Metabolic syndrome is significantly associated with overactive bladder in female patients, according to a study published in the January issue of Urology.

Hakki Uzun, M.D., and Orhan Ünal Zorba, from the Rize University School of Medicine in Turkey, and colleagues investigated the relevance of metabolic syndrome in the cause and development of overactive bladder in female patients. A total of 313 patients with overactive bladder, and 208 patients (controls) with other urologic complaints, but without overactive bladder, were enrolled in the study. Metabolic syndrome was defined using the International Diabetes Federation criteria.

The investigators diagnosed metabolic syndrome in 64 percent of patients with overactive bladder, and 35 percent of controls, with a statistically significant difference between the groups. Compared with controls, the overactive bladder group had significantly larger waist circumference, greater body mass index, greater incidence of hypertension, and lower high-density lipoprotein levels.

"The metabolic syndrome correlated highly with the overactive bladder in female patients. The metabolic syndrome can be an etiologic pathway for the onset of symptoms, and avoiding a sedentary lifestyle and poor eating habits with weight loss or improvement in the treatment targeted toward the metabolic syndrome might be a worthwhile research area to develop into a potential therapeutic modality," the authors write.

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