Increase in second year post-surgery; linked to Roux-en-Y gastric bypass, male sex, younger age
MONDAY, June 18 (HealthDay News) -- Patients who undergo bariatric surgery have an increased risk of alcohol use disorder (AUD) in the second year after surgery, according to a study published online June 18 in the Journal of the American Medical Association to coincide with presentation at the annual meeting of the American Society for Metabolic & Bariatric Surgery, held from June 17 to 22 in San Diego.
To examine the prevalence of pre- and postoperative AUD and predictors of postoperative AUD, Wendy C. King, Ph.D., from the University of Pittsburgh, and colleagues conducted a prospective cohort study involving 1,945 adults (78.8 percent female; median age, 47 years) among 2,458 participants who underwent bariatric surgery at 10 U.S. hospitals.
The researchers found that the there was no significant difference in the prevalence of AUD symptoms from one year before to one year after surgery (7.6 versus 7.3 percent; P = 0.98), but the prevalence was significantly increased in the second year after surgery (9.6 percent; P = 0.01). Increased odds of AUD after bariatric surgery were independently associated with male gender (adjusted odds ratio [aOR], 2.14); younger age (aOR per 10 years younger with or without preoperative AUD, 1.31 and 1.95, respectively); smoking (aOR, 2.58); regular alcohol consumption (two or more drinks per week: aOR, 6.37); recreational drug use (aOR, 2.38); AUD (at age 45: aOR, 11.14); lower sense of belonging (aOR, 1.09); and Roux-en-Y gastric bypass (RYGB) procedure (aOR, 2.07).
"Regardless of alcohol history, patients should be educated about the potential effects of bariatric surgery, in particular RYGB, to increase the risk of AUD," the authors write.
Two authors disclosed financial ties to the pharmaceutical industry.
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