Keywords

refractory pyoderma gangrenosum, Apligraf, systemic immunosuppressive agents, Apligraf and systemic immunosuppressive agents

 

Authors

  1. Duchini, Giacomo MD
  2. Itin, Peter MD, Prof
  3. Arnold, Andreas MD

Abstract

Pyoderma gangrenosum (PG) is a rare inflammatory ulcerative skin disease. A case of refractory PG treated with a combination of immunosuppression and Apligraf (Organogenesis, Canton, Massachusetts) is presented.Under infliximab, systemic corticosteroids, and Apligraf, the wound showed a slow but complete healing. The authors demonstrated the potential benefits of Apligraf in the healing of PG.