Buy this article for $3.95

Have a coupon or promotional code? Enter it here:

When you buy this article you'll get access to the ePub version, a downloadable PDF, and the ability to print the full article.

Source:

Nursing2015

December 2006, Volume 36 Number 12 , p 24 - 24

Authors

  • Cathy Flasar RN, BC, FNP, MSN
  • Joan D. Wentz RN, MSN

Abstract


Flasar, Cathy RN, BC, FNP, MSN; Wentz, Joan D. RN, MSN

Many of my older patients have osteoarthritis. Can they safely use selective or nonselective nonsteroidal anti-inflammatory drugs (NSAIDs) to treat their chronic pain? - —A.D., MD.

Cathy Flasar, RN, BC, FNP, MSN and Joan D. Wentz, RN, MSN, reply: Your concern is understandable. Two selective NSAIDs, the cyclooxygenase-2 (COX-2) inhibitors rofecoxib (Vioxx) and valdecoxib (Bextra), were withdrawn from the market because of cardiovascular risks. Celecoxib (Celebrex) is the only COX-2 inhibitor available in the United States. Nonselective NSAIDs such as ibuprofen are available over the counter (OTC); others like diclofenac are available by prescription.

Like the other COX-2 inhibitors, celecoxib has been found to raise cardiovascular risks, but the risk is dose-related. (The higher the dose, the greater the risk.) Ibuprofen and diclofenac appear to carry the lowest cardiovascular risk of all the NSAIDs except aspirin.

Current ...

To continue reading, buy this article for just $3.95.

Have a coupon or promotional code? Enter it here: