View Entire Collection
By Clinical Topic
By State Requirement
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
THURSDAY, Sept. 25 (HealthDay News) -- There is a compelling rationale for clinicians to critically analyze evidence-based guidelines when using implantable cardioverter-defibrillators (ICDs) for the prevention of sudden cardiac death, according to a report published in the Sept. 30 issue of the Journal of the American College of Cardiology.
In a critical appraisal, Roderick Tung, M.D., of Beth Israel Deaconess Medical Center in Boston, and colleagues reviewed scientific literature for the benefits and potential hazards of ICD therapy.
The findings suggest that the efficacy of ICD therapy has been overestimated in clinical trials while the cost of therapy as well as adverse effects have been ignored. The authors associate ICDs with morbidity and poor quality of life due to infection, shocks, potential for inducing arrhythmia, device malfunction and procedural complications. Nonetheless, multiple trials have generated consistent results over more than 10 years with a 20 to 30 percent reduction in total mortality and improved survival in patients with left ventricular dysfunction, according to an accompanying commentary by Andrew E. Epstein, M.D., of the University of Alabama at Birmingham.
"Although we all freely admit that there are problems with ICDs, the weight of evidence supports their use for the indications listed in appropriate patients," based on the 2008 Device-Based Therapy Guidelines, Epstein writes.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top