View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
FRIDAY, Feb. 27 (HealthDay News) -- A newly developed risk score based on readily available clinical factors can predict an individual's absolute risk of developing atrial fibrillation, allowing high-risk individuals to be targeted for prevention, according to research published in the Feb. 28 issue of The Lancet.
Renate B. Schnabel, M.D., of the Framingham Heart Study in Framingham, Mass., and colleagues evaluated 8,044 clinical examinations from 4,764 study participants (aged 45 to 95 years) performed between 1968 and 1987. Study participants were then followed for a maximum of 10 years.
Using several clinical factors, the investigators developed a clinically significant risk score for developing atrial fibrillation within 10 years. The clinical factors included age, sex, body mass index, systolic blood pressure, hypertension medication, the presence of a clinically significant cardiac murmur and heart failure. The risk score was much higher in individuals over 65 years than in those younger than 65 (27 percent versus 1 percent had more than a 15 percent risk of developing atrial fibrillation in 10 years). Echocardiograph only modestly improved the risk prediction model.
The authors of an accompanying comment state "by evaluating the incremental predictive value of genetic or biological markers beyond the clinical variables in the current model, we should arrive at a better understanding of their relative importance in the development of atrial fibrillation and a better predictive tool."
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top