First-Degree Atrioventricular Block Shows Heightened Risk

Patients have elevated long-term risk of atrial fibrillation, pacemaker implantation, and death
By Rick Ansorge
HealthDay Reporter

TUESDAY, June 23 (HealthDay News) -- Patients with first-degree atrioventricular block may have an increased risk of atrial fibrillation, pacemaker implantation, and all-cause mortality, according to a study published in the June 24 issue of the Journal of the American Medical Association.

Susan Cheng, M.D., of the Framingham Heart Study in Massachusetts, and colleagues studied 7,575 subjects who underwent baseline examinations in 1968 to 1974. During follow-up through 2007, they observed 481 cases of atrial fibrillation, 124 cases requiring pacemaker implantation, and 1,739 deaths.

The researchers' multivariable analyses showed that each 20-millisecond increment in PR was associated with an increased risk of atrial fibrillation, pacemaker implantation, and death (hazard ratios, 1.11, 1.22, and 1.08, respectively). Overall, they found that patients with first-degree atrioventricular block had a two-fold adjusted risk of atrial fibrillation, a three-fold adjusted risk of pacemaker implantation, and a 1.4-fold adjusted risk of all-cause mortality.

"These results suggest that the natural history of first-degree atrioventricular block is not as benign as previously believed," the authors conclude. "Additional studies are needed to determine appropriate follow-up for individuals found to have prolongation of the PR interval on a routine electrocardiogram."

Abstract
Full Text (subscription or payment may be required)

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

What internal motivators drive RNs to pursue a BSN?
Nursing2014 , October 2014
Free access will expire on November 24, 2014.


Breast Cancer Risk Assessment in Primary Care
MCN, The American Journal of Maternal/Child Nursing, September/October 2014
Free access will expire on November 10, 2014.


Nurses spurring innovation
Nursing Management, October 2014
Free access will expire on November 10, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events