Best Treatment for Lower Extremity Sarcoma Unknown

Need for more studies comparing impact, benefit of limb salvage surgery with amputation
By Lisa Cockrell, PhD
HealthDay Reporter

MONDAY, Aug. 10 (HealthDay News) -- Despite a lower prevalence of amputations, limb salvage surgery may not offer a more effective outcome for health-related quality of life (HRQoL) for younger individuals with bone and soft tissue sarcomas of the leg, according to a review published online Aug. 10 in Cancer.

Ronald D. Barr, M.D., of McMaster University in Hamilton, Canada, and colleague performed a review of studies of individuals who were diagnosed with cancer as a child. Although there is a lack of robust data, the present evidence largely suggests that HRQoL is similar between those patients who underwent limb salvage surgery and those who had limb amputations. Some reports actually suggest improved HRQoL with amputation.

In an economic evaluation of surgical alternatives for younger individuals with tumors in the lower extremities, the up-front costs associated with salvaging the limb were found to likely be a trade-off for the maintenance costs associated with limb amputation. The authors of the review conclude that a more formal economic evaluation would likely help guide future decisions regarding limb salvage surgery.

"Although it appears that the number of amputations per year has decreased with time, it cannot be assumed that limb salvage surgery will offer a better functional outcome and HRQoL for young people with bone and soft tissue sarcomas of the lower limb. Although this challenge is clearly a moving target, formal economic evaluation would make a useful contribution to future decision making by patients and their health care providers, surgeons, and others alike," the authors write.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95


The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95


Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.


Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.


Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events