View Entire Collection
By Clinical Topic
By State Requirement
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
TUESDAY, Oct. 27 (HealthDay News) -- In patients with diabetes mellitus (DM) and Alzheimer's disease, the presence of DM slows the rate of cognitive decline associated with Alzheimer's disease, according to a prospective, multi-center study in the Oct. 27 issue of Neurology.
Caroline Sanz, M.D., of University Toulouse III in France, and colleagues conducted a study of 608 patients with a probable diagnosis of Alzheimer's disease and a Mini-Mental State Examination (MMSE) score between 10 and 26. Patients were assessed at baseline for DM and were followed up for 52 months with cognitive function assessed twice a year.
At baseline, the researchers found that 10.4 percent of the participants had DM, and baseline scores on the MMSE were the same for this group as they were for those without DM. However, among the DM group, cognitive decline was slower.
"This study confirms the unexpected effect of DM on the rate of cognitive decline in one of the largest cohorts of patients with Alzheimer's disease so far studied and over a four-year period of follow-up," the authors write. "Future studies will need to address the potential impact of DM in the cerebral aging process and to assess the neuropathologic variations in patients with Alzheimer's disease with DM."
Several authors reported financial and consulting relationships with pharmaceutical companies.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top