Ultraviolet Light Exposure and Renal Cancer Risk Assessed

Study finds inverse association between occupational exposure and renal cancer in men
By Jane Parry
HealthDay Reporter

MONDAY, March 8 (HealthDay News) -- Occupational exposure to sunlight may be inversely associated with the risk of renal cell carcinoma (RCC) in men, according to a study published online March 8 in Cancer.

Sara Karami, Ph.D., of the National Cancer Institute in Bethesda, Md., and colleagues conducted a large case control study to assess occupational exposure to ultraviolet (UV) light and risk of RCC, comprising 1,097 RCC patients and 1,476 controls in four central and eastern European countries. The researchers used indices of occupational UV exposure and personal interviews to collect demographic and lifetime UV exposure information.

The researchers found that increasing occupational exposure to UV light was associated with a 24 to 38 percent lower risk of RCC among the male participants, but no such association was found among women. Men at highest latitudes, who were therefore exposed to more intense sunlight, had a 71 to 73 percent lower risk of the disease.

"Our findings, which are supported by most UV/cancer studies, demonstrated that occupational UV exposure is associated with renal cancer risk among men," the authors write. "Additional studies that consider recreational UV exposure and behavioral differences, in an effort to reduce exposure misclassification, are warranted, particularly among women."

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