View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
TUESDAY, April 6 (HealthDay News) -- Adolescents with the minor A allele of the fat mass- and obesity-associated gene (FTO) rs9939609 polymorphism are at high risk of obesity, but that risk can be overcome by an hour or more of daily exercise, according to a study in the April issue of the Archives of Pediatrics & Adolescent Medicine.
Jonatan R. Ruiz, Ph.D., of Karolinska Institutet in Huddinge, Sweden, and colleagues studied a cohort of 752 adolescents in the Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional Study.
Overall, the researchers found that the presence of the minor A allele of the FTO polymorphism was associated with higher body mass index and body fat percentage, as well as greater waist circumference. However, the polymorphism's effect was reduced among adolescents who performed at least 60 minutes a day of moderate to vigorous physical activity, in compliance with U.S. Department of Health and Human Services recommendations, compared to those who did not (+0.17 versus +0.65 per risk allele for body mass index, +0.40 versus +1.70 percent per risk allele for body fat percentage, and +0.60 versus +1.15 cm per risk allele for waist circumference).
"These findings have important public health implications and indicate that meeting the physical activity recommendations may offset the genetic predispositions to obesity associated with the FTO polymorphism in adolescents," the authors write.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top