View Entire Collection
By Clinical Topic
By State Requirement
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
WEDNESDAY, May 12 (HealthDay News) -- A high body mass index (BMI) and, to some extent, specific lifestyle factors may explain a substantial part of the association between family history of diabetes and type 2 diabetes risk, according to research published in the April issue of Diabetes Care.
To determine how much of the association between a family history of diabetes and risk of developing type 2 diabetes can be explained by excess adiposity and lifestyle risk factors, Esther Van't Riet, of the Harvard School of Public Health in Boston, analyzed 5,101 cases of type 2 diabetes in 20 years of follow-up from participants in the Nurses' Health Study cohort.
The researchers found that, compared to those with no family history, the age-adjusted relative risk of type 2 diabetes in those with a family history was 2.27. Subjects with a family history also had a higher BMI and were more likely to have obese parents. The researchers determined that BMI explained 21.1 percent of the link between type 2 diabetes risk and family history. Lifestyle factors that explained part of the risk included intake of alcohol, red meat, and sugar-sweetened beverages.
"A substantial part of the association between having a family history of diabetes and 20-year incidence of type 2 diabetes could be explained by excess adiposity, whereas dietary factors might also play a role. Further studies on this topic with more detailed measures of family history of diabetes, adiposity, and lifestyle factors are warranted," the authors write.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top