View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
MONDAY, May 10 (HealthDay News) -- High blood pressure (BP) and greater BP fluctuations are associated with an increased risk for cerebrovascular disease in older adults, according to research published in the May issue of the Archives of Neurology.
Adam M. Brickman, Ph.D., of Columbia University in New York City, and colleagues conducted an epidemiological study of 686 non-demented older adults whose BP measurements were taken during three study visits at two-year intervals to determine the association between BP and long-term fluctuation in BP with cerebrovascular disease. The subjects were divided into four groups defined as below or above the group median and divided again as below or above the median standard deviation (SD).
The researchers found that white matter hyperintensity volume grew in the four groups in a linear matter, being lowest in the lowest mean/lowest SD group and highest in the highest mean/highest SD group. The frequency of brain infarctions also increased across the groups (22 to 41 percent).
"Compared with individuals with low BP and low fluctuations in BP, the risk of cerebrovascular disease increased with higher BP and BP fluctuations. Given that cerebrovascular disease is associated with disability, these findings suggest that interventions should focus on long-term fluctuating BP and elevated BP," the authors conclude.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top