View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
THURSDAY, June 3 (HealthDay News) -- The stress of caring for a spouse with Alzheimer's disease may increase the risk of cardiovascular events due to impaired endothelial functioning, according to research published in the June 8 issue of the Journal of the American College of Cardiology.
To examine the relationship between chronic caregiving stress and endothelial function, Brent T. Mausbach, Ph.D., of the University of California San Diego in La Jolla, and colleagues analyzed 78 elderly individuals, 55 of whom were providing in-home care to a spouse with Alzheimer's disease, and 23 of whom were living with a healthy, non-demented spouse.
The researchers found a significant association between Clinical Dementia Rating scores and flow-mediated dilation (FMD); subjects who served as caregivers to a spouse with moderate to severe dementia had significantly worse FMD than those whose spouses had mild or no dementia. There was also a significant relation of FMD to number of years caregiving in the caregiver group.
"These results suggest that the chronic stress of caregiving is associated with impaired endothelial function, which may be a potential mechanistic link to the observed increased risk of cardiovascular disease in elderly caregivers," the authors write.
Two study authors disclosed financial ties to pharmaceutical companies.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top