Stroke Recurrence and Severity Higher in Mexican Americans

In atrial fibrillation patients in this group, all-cause mortality similar to that of non-Hispanic whites
By Beth Gilbert
HealthDay Reporter

THURSDAY, Sept. 9 (HealthDay News) -- Mexican Americans (MAs) with atrial fibrillation who experience ischemic stroke or transient ischemic attack (TIA) are at a higher risk of stroke recurrence and more severe recurrences than non-Hispanic whites (NHWs), but all-cause mortality appears to be similar between the two groups, according to a study published online Sept. 9 in Stroke.

Jennifer R. Simpson, M.D., of the University of Michigan in Ann Arbor, and colleagues compared stroke recurrence and all-cause mortality among 88 MAs and 148 NHWs who had atrial fibrillation and had experienced ischemic stroke/TIA.

The investigators found that MAs had an increased risk of stroke recurrence compared to NHWs, which remained after adjusting for age and gender (hazard ratio, 2.46). Kaplan-Meier estimates of survival without stroke recurrence risk at 28 days and one year were 0.99 and 0.85 in MAs and 0.98 and 0.96 in NHWs, respectively. Recurrent stroke severity was increased among MAs compared to NHWs. However, the researchers showed that all-cause mortality did not differ between MAs and NHWs in unadjusted analysis or after they adjusted for demographic and clinical factors.

"Aggressive stroke prevention measures are warranted in this population, and further study is needed to investigate reasons for the higher risk of recurrence and severity in MAs," the authors write.

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