View Entire Collection
By Clinical Topic
By State Requirement
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
MONDAY, Sept. 27 (HealthDay News) -- Compared to usual care, a mindfulness-based intervention (MBI) appears to improve health-related quality of life (HRQOL), depression, and fatigue among individuals with multiple sclerosis (MS), according to a study in the Sept. 28 issue of Neurology.
Paul Grossman, Ph.D., of University Hospital Basel in Switzerland, and colleagues randomized 150 patients with relapsing-remitting or secondary progressive MS to a structured eight-week MBI or usual care. The primary outcomes were HRQOL, depression, and fatigue.
Intention-to-treat analysis revealed that, compared to usual care, MBI improved nonphysical dimensions of primary outcomes at post-intervention and follow-up. The investigators also found that post-intervention and follow-up effects remained significant when analyses were repeated among subgroups with clinically relevant levels of pre-intervention depression, fatigue, or anxiety.
"The results of this solidly designed study underscore the importance of treatment directed at quality-of-life issues in patients with MS, and provide level III evidence that mindfulness-based meditation is a helpful therapeutic option," write the authors of an accompanying editorial.
The study was funded in part by Sanofi-Aventis, Merck Serono, and Biogen-Dompé AG. Study authors disclosed financial ties to these and other pharmaceutical companies.
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top