View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
WEDNESDAY, Sept. 29 (HealthDay News) -- Oseltamivir (Tamiflu) treatment appears to be effective in preventing the development of radiographically confirmed pneumonia as well as reducing duration of fever and viral RNA shedding among patients with 2009 H1N1 infection, according to a study published online Sept. 28 in BMJ.
Hongjie Yu, M.D., of the Chinese Centre for Disease Control and Prevention in Beijing, and colleagues retrospectively reviewed medical charts of 1,291 patients with confirmed 2009 H1N1 identified through the national surveillance system in China between May and July 2009.
The investigators found that fever (64 percent), cough (67 percent), sore throat (33 percent), sputum (19 percent), and rhinorrhoea (18 percent) were the most common symptoms. In addition, 110 of 920 patients who underwent chest radiography had abnormal findings consistent with pneumonia. The median number of days of shedding after onset of symptoms was five. Oseltamivir was used to treat 76 percent of patients from a median of the third day of symptoms, with treatment significantly protective against later development of radiographically confirmed pneumonia (odds ratio, 0.12). In addition, treatment with oseltamivir started within two days of the onset of symptoms reduced the duration of fever and viral RNA shedding.
"Though these patients benefited from treatment, the findings should be interpreted with caution as the study was retrospective and not all patients underwent chest radiography," the authors write.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top