View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
THURSDAY, Oct. 7 (HealthDay News) -- Women with ductal carcinoma in situ (DCIS) and mammographically dense breasts may have an increased risk of subsequent breast cancer, particularly in the opposite breast, according to research published in the October issue of Cancer Epidemiology, Biomarkers & Prevention.
Laurel A. Habel, Ph.D., of Kaiser Permanente in Oakland, Calif., and colleagues analyzed data from 935 patients with DCIS who were treated with breast-conserving surgery. The researchers reviewed density on ipsilateral mammograms from the index DCIS, and patients were followed for a median 103 months.
The researchers found that 18 percent of patients had a subsequent breast cancer in the same breast and 6 percent had a new primary cancer in the opposite breast. Those with the upper 20 percent of total area of density had higher risk of invasive disease in either breast (hazard ratio, 2.1) than patients in the bottom 20 percent, as well as higher risk of any cancer in the same or opposite breast (hazard ratios, 1.7 and 3.0, respectively).
"Together with the findings from two other reports, our study results suggest that mammographic density assessment at diagnosis may aid in the prediction of risk for second cancers among women with DCIS. This information may be important to patients and doctors when making treatment decisions, especially given recent data suggesting increasing rates of contralateral prophylactic mastectomy in DCIS patients," the authors conclude.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top