View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
FRIDAY, Oct. 15 (HealthDay News) -- Coronary artery calcium (CAC) levels can be used to fine-tune coronary heart disease (CHD) risk assessment in elderly people with no disease symptoms, according to a study in the Oct. 19 issue of the Journal of the American College of Cardiology.
Suzette E. Elias-Smale, M.D., of Erasmus Medical Center in Rotterdam, the Netherlands, and colleagues followed 2,028 elderly subjects without CHD symptoms for a median 9.2 years, during which 135 nonfatal myocardial infarctions and CHD deaths occurred. First the subjects were classified into low-, intermediate-, and high-risk categories in accordance with a Framingham risk model, and then the researchers added CAC levels (measured in Agatston units) to the risk model, assessed the impact of CAC on risk recalculation, and computed CAC cutoff values for risk reclassification.
Fifty-one percent of men and 53 percent of women initially classified as intermediate-risk were reclassified as a result of the inclusion of CAC levels. Among men, 30 percent of those initially at intermediate risk were moved to the low-risk category, and 21 percent were moved to the high-risk category. Among women, 29 percent of those initially at intermediate risk were moved to a lower-risk category and 24 percent were moved to a higher-risk category.
"In a general population of elderly patients at intermediate CHD risk, CAC scoring is a powerful method to reclassify persons into more appropriate risk categories. Empirically derived CAC cut-off values at which persons at intermediate risk reclassified to either high or low risk were 615 and 50 Agatston units, respectively," the authors write.
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top