AACR: Soy Components Linked to Lower Risk of Breast Cancers

Study assesses total and specific isoflavones, tumor characteristics, and menopausal status

TUESDAY, Nov. 9 (HealthDay News) -- Phytoestrogens found in soy may influence the risk of some types of breast cancer, according to research presented at the American Association for Cancer Research's Frontiers in Cancer Prevention Research Conference, held from Nov. 7 to 10 in Philadelphia.

Anne M. Weaver, of the Roswell Park Cancer Institute in Buffalo, N.Y., and colleagues analyzed data from 683 women with newly diagnosed breast cancer and 611 women without a history of the disease. The researchers calculated their intake of total and specific isoflavones from food-frequency questionnaires.

The researchers found that cases in the highest tertile of isoflavone intake had roughly 30 percent lower odds of an invasive tumor and 60 percent lower odds of a grade 1 tumor than those in the lowest tertile. In premenopausal women, greater intakes of total isoflavone, daidzein, genistein, and glycetein were associated with roughly 70 percent lower odds of a tumor greater than 2 cm in size. Premenopausal women in the highest tertile of total isoflavone and genistein intake (versus the lowest) had roughly 60 percent lower odds of stage II breast cancer.

"In this study, there is little evidence that isoflavones are associated with indicators associated with poor prognosis or recurrence, suggesting that these compounds may operate through mechanisms specific to the biologic heterogeneity of the tumor. Further research is warranted to address the impact of tumor heterogeneity in studies of isoflavones and breast cancer," the authors conclude.

Press Release
More Information

Copyright © 2010 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Debunking Three Rape Myths
Journal of Forensic Nursing, October/December 2014
Expires: 12/31/2016 CE:2.5 $24.95


Drug updates and approvals: 2014 in review
The Nurse Practitioner, 13December 2014
Expires: 12/31/2016 CE:3 $27.95


Can Food Processing Enhance Cancer Protection?
Nutrition Today, September/October 2014
Expires: 10/31/2016 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events