Low Birth Weight Impacts Adult Arterial Proportions

Adults born at very low birth weight may benefit from targeted cardiovascular disease prevention

FRIDAY, Jan. 28 (HealthDay News) -- Higher intima-media thickness (IMT) in young adults born with very low birth weight (VLBW) may be linked to an increased risk for cardiovascular disease, according to a study published online Jan. 24 in Pediatrics.

Petteri Hovi, M.D., from the Hospital for Children and Adolescents in Helsinki, Finland, and colleagues measured the stiffness and IMT thickness of the right carotid artery and flow-mediated dilatation (FMD) of the right brachial artery in 92 VLBW subjects and 68 control subjects between the ages of 18 and 27.

The researchers found that subjects with a VLBW had a 0.5 percent unit higher IMT relative to lumen size and a 1.1 percent unit higher FMD (P = 0.06). Carotid stiffness, IMT, and FMD, when analyzed as the absolute change in millimeters, were all similar between the two groups. They also found that among those patients with VLBW, every 100-gram-greater weight gain during the first two weeks postnatal predicted a 1.1 percent unit higher FMD later in adulthood, and that more rapid growth in the early postnatal period was associated with better endothelial function.

"With a number of risk factors for cardiovascular disease operating in young adulthood, our data suggest that those born at VLBW would benefit from targeted prevention of cardiovascular disease," the authors write.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Debunking Three Rape Myths
Journal of Forensic Nursing, October/December 2014
Expires: 12/31/2016 CE:2.5 $24.95


Drug updates and approvals: 2014 in review
The Nurse Practitioner, 13December 2014
Expires: 12/31/2016 CE:3 $27.95


Can Food Processing Enhance Cancer Protection?
Nutrition Today, September/October 2014
Expires: 10/31/2016 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events