H1N1 Vaccine Appears Safe

Surveillance identifies few serious adverse events, no increased risk of Guillain-Barré

WEDNESDAY, Feb. 2 (HealthDay News) -- Adverse events associated with influenza A (H1N1) vaccine appear to be limited and relatively rare, and there is no evidence of an increased risk of Guillain-Barré syndrome associated with the virus, according to research published online Feb. 2 in the New England Journal of Medicine.

Xiao-Feng Liang, M.D., Ph.D., of the Chinese Center for Disease Control and Prevention in Beijing, and colleagues collected data on 89.6 million doses of H1N1 vaccine administered in 2009 and 2010 to assess the safety of China's vaccination program.

The researchers identified 8,067 adverse events, or 90 per one million doses. Adverse events were higher in children aged 9 or younger and lower in adults over 60, at 130.6 and 31.4 per one million doses, respectively. A total of 6,552 of the adverse events (81.2 percent) were confirmed as vaccine reactions, and 13.4 percent of the adverse events were identified as rare and more serious; almost all of these were allergic reactions. The rate of Guillain-Barré syndrome reported -- 0.1 per one million doses -- was lower than China's background rate.

"No pattern of adverse events that would be of concern was observed after the administration of influenza A (H1N1) vaccine, nor was there evidence of an increased risk of the Guillain-Barré syndrome," the authors write.

Full Text

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95

The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95

Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.

Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.

Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events