Cardiac Resynchronization Aids Less Symptomatic Patients

Reduces heart failure morbidity and mortality, regardless of symptom severity

WEDNESDAY, Feb. 16 (HealthDay News) -- Cardiac resynchronization therapy (CRT), which reduces morbidity and mortality in patients with advanced heart failure, also reduces mortality and frequency of heart failure-related hospitalizations in patients with milder heart failure, according to a review published online Feb. 15 in the Annals of Internal Medicine.

Nawaf S. Al-Majed, M.B.B.S., of the University of Alberta in Edmonton, Canada, and colleagues conducted a systematic review of 25 randomized controlled trials of CRT. They investigated the impact of CRT in less symptomatic patients (New York Heart Association [NYHA] class I or II) compared to patients with advanced heart failure.

The researchers found that CRT reduced all-cause mortality and heart failure hospitalizations (relative risks, 0.83 and 0.71, respectively) in NYHA class I and II patients, but without improvements in functional outcomes or quality of life. In NYHA III and IV patients, CRT also reduced mortality and hospitalizations (relative risks, 0.78 and 0.65, respectively), and it improved functional outcomes. The implant success rate was 94.4 percent. The researchers noted a 0.3 percent peri-implant death rate, a 3.2 percent mechanical complication rate, a 6.2 percent lead problem rate, and a 1.4 percent infection rate.

"Our data support the expansion of indications for CRT to incorporate less symptomatic patients with heart failure who have left ventricular ejection fraction <30 percent, QRS duration >120 msec, and are in sinus rhythm," the authors write.

Abstract
Full Text
Editorial

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95


The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95


Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.


Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.


Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events