Improvement in Fibromyalgia Pain Scale Quantified

Two-point improvement on Brief Pain Inventory implies meaningful pain reduction

TUESDAY, March 8 (HealthDay News) -- A two-point improvement on the Brief Pain Inventory (BPI) represents the minimum clinically important difference (MCID) for patients with fibromyalgia pain, corresponding to a 30 to 35 percent improvement from baseline, according to a study published online Feb. 10 in Arthritis Care & Research.

Philip J. Mease, M.D., of the University of Washington School of Medicine in Seattle, and colleagues used data from four studies evaluating duloxetine as a treatment for fibromyalgia. They estimated the MCID for the BPI average pain item score and the BPI severity score by anchoring them against the Patient Global Impression of Improvement scale.

The researchers determined that an approximately two-point improvement on both the BPI average pain item and severity scores represented the MCID. These MCIDs corresponded to a 30 to 35 percent improvement in baseline pain in both scores.

"These findings may be beneficial for use in designing clinical trials in which the BPI is used to evaluate improvements in pain severity," the authors write.

The study received financial support from Eli Lilly and Company and Boehringer Ingelheim GmbH.

Full Text (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95

The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95

Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.

Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.

Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events