Breast Cancer History Lowers Accuracy of Mammogram

Mammogram's sensitivity lower in the initial five-year period after the first cancer

TUESDAY, Feb. 22 (HealthDay News) -- Mammography screening for breast cancer may be less accurate among women with a personal history of breast cancer (PHBC), despite a higher underlying cancer rate, relative to women without PHBC, according to a study published in the Feb. 23 issue of the Journal of the American Medical Association.

Nehmat Houssami, M.B.B.S., Ph.D., of the University of Sydney in Australia, and colleagues investigated the accuracy of mammography breast cancer screening among women with PHBC. They studied screening mammograms in women with and without a history of early-stage breast cancer and calculated the accuracy of the screening test (based on the scan's final assessment), the cancer detection rate, the interval cancer rate, and the stage at diagnosis.

The researchers found that, despite higher rates of cancer, cancer detection, and interval cancer, the mammogram's sensitivity was significantly lower among PHBC women compared to non-PHBC women (65.4 versus 76.5 percent). Screening sensitivity and detection was higher for in-situ tumors compared to invasive cancer in PHBC women. Among the PHBC women, the mammogram's sensitivity was lower in the initial five-year period after the first cancer, and subsequently increased. Most of the cancers detected in both groups of women were at the early stage.

"Screening mammography detects early-stage breast cancers in PHBC women but has lower accuracy relative to screening women without PHBC. Despite a relatively high interval cancer rate, interval cancers in PHBC women had generally favorable stage distributions," the authors write.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Debunking Three Rape Myths
Journal of Forensic Nursing, October/December 2014
Expires: 12/31/2016 CE:2.5 $24.95


Drug updates and approvals: 2014 in review
The Nurse Practitioner, 13December 2014
Expires: 12/31/2016 CE:3 $27.95


Can Food Processing Enhance Cancer Protection?
Nutrition Today, September/October 2014
Expires: 10/31/2016 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events