View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
FRIDAY, March 11 (HealthDay News) -- Symptoms of depression are associated with subsequent adverse outcomes in patients with renal disease, according to a study published online March 10 in the Clinical Journal of the American Society of Nephrology.
Willem J. Kop, Ph.D., from the University of Maryland in Baltimore, and colleagues determined the association of depressive symptoms with decline in renal function, new-onset chronic kidney disease (CKD), end-stage renal disease (ESRD), or hospitalization with acute kidney injury (AKI). Depressive symptoms were measured in 5,785 patients using the 10-item Centers for Epidemiologic Studies Depression scale. Renal function was measured during an average follow-up of 10.5 years.
The researchers found that depressed participants had a higher prevalence of CKD at baseline compared to those participants who were not depressed. Unadjusted models linked depression with a subsequent risk of rapid decline in estimated glomerular filtration rate, incident ESRD, and AKI. In multivariable analyses after adjusting for traditional renal disease risk factors, the only remaining significant association was that of depressive symptoms with AKI.
"The association of depressive symptoms with long-term risk of AKI is independent of a broad range of covariates and therefore clinically important," the authors write. "These findings show that the association between depression with adverse renal outcomes is not merely an epiphenomenon of underlying symptomatic renal disease."
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top