View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
WEDNESDAY, March 16 (HealthDay News) -- Early- and late-onset diabetes are associated with an increased risk of major coronary heart disease (CHD) events and mortality, with early-onset diabetes equivalent in risk to a prior myocardial infarction (MI), according to a study published in the March 14 issue of the Archives of Internal Medicine.
S. Goya Wannamethee, Ph.D., from University College London, and colleagues examined the influence of age of onset and duration of diabetes on cardiovascular disease (CVD) risk, and all-cause mortality in 4,045 men aged 60 to 79. Participants were followed up for an average of nine years during which time there were 372 major CHD events, 455 CVD deaths, and 1,112 deaths from all causes. Men were classified according to their history of MI and diabetes.
The investigators found that, compared to men without diabetes and with no CHD, both early and late onset of diabetes were linked with a significantly elevated risk of major CHD events and all-cause mortality, even after adjusting for traditional and novel risk factors. The adjusted relative risks for major CHD events were 1.00 for men with no history of diabetes or MI; 1.54 for those with late-onset diabetes; 2.39 for those with early-onset diabetes; and 2.51 for men without diabetes with prior MI.
"Early onset of diabetes (associated with more than a decade of mean duration of diabetes) appears to be equivalent in risk of CVD to a previous MI," the authors write.
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top