AACR: Human Papillomavirus Tied to Lung Cancer

High-risk HPV antibodies increased in lung cancer cases compared to controls

MONDAY, April 4 (HealthDay News) -- Several high-risk forms of human papillomavirus (HPV) antibodies may be associated with an increased risk of lung cancer, according to research presented at the annual meeting of the American Association for Cancer Research, held April 2 to 6 in Orlando, Fla.

Devasena Anantharaman, Ph.D., of the International Agency for Research on Cancer in Lyon, France, and colleagues determined the presence of several high-risk and low-risk types of HPV using serological tests in 1,633 individuals with lung cancer and 2,729 matched controls from six central European countries.

The investigators found that antibodies to proteins in eight types of high-risk HPV were significantly increased among individuals with lung cancer. However, a low prevalence of antibodies to all types of HPV tested was found among controls. The investigators also found that smoking did not account for this effect, as the results were consistent in current smokers, former smokers, and those who never smoked.

"While a number of previous studies have demonstrated the presence of HPV in lung cancer, their statistical power has been limited by small average sample size and variations in methodology," Anantharaman said in a statement. "We know that HPV can reach the lung, but whether HPV can cause frank malignancies is a question we hope to answer."

Abstract No. 1890
More Information

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95


The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95


Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.


Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.


Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events