View Entire Collection
By Clinical Topic
By State Requirement
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
TUESDAY, Aug. 16 (HealthDay News) -- Chinese herbal decoction maxingshigan-yinqiaosan, alone or in combination with oseltamivir, is associated with a reduced time to fever resolution in patients with H1N1 influenza virus infection, according to a study published in the Aug. 16 issue of the Annals of Internal Medicine.
Chen Wang, M.D., Ph.D., from the Ministry of Health in Beijing, and colleagues compared the efficacy and safety of maxingshigan-yinqiaosan with oseltamivir for the treatment of uncomplicated H1N1 influenza. A total of 410 adults between the ages of 15 and 59 years with confirmed H1N1 influenza received either oseltamivir (75 mg twice daily) alone, a decoction of maxingshigan-yinqiaosan (200 mL, four times daily), oseltamivir plus maxingshigan-yinqiaosan, or no treatment (control) for a period of five days. Time to fever resolution was the primary outcome measure, and symptom scores and viral shedding using real-time reverse transcriptase polymerase chain reaction were the secondary outcome measures.
The investigators found that oseltamivir (34 percent), maxingshigan-yinqiaosan (37 percent), and the combination treatment of oseltamivir plus maxingshigan-yinqiaosan (47 percent) significantly reduced the median time to fever resolution compared to the control group. The combination treatment reduced time to fever resolution by 19 percent when compared to oseltamivir alone. The decrease in symptom scores was not significantly different in the intervention or control groups. Nausea and vomiting were reported in two patients receiving maxingshigan-yinqiaosan.
"Oseltamivir and maxingshigan-yinqiaosan, alone and in combination, reduced time to fever resolution in patients with H1N1 influenza virus infection," the authors write.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top