Racial Discrimination Tied to RBC Oxidative Stress Levels

African-Americans who face racial discrimination have higher levels of oxidative stress than whites

THURSDAY, Sept. 22 (HealthDay News) -- Self-reported racial discrimination is significantly associated with red blood cell (RBC) oxidative stress, with the association remaining statistically significant for African-Americans but not whites, after stratifying by race, according to a study published online Sept. 13 in the International Journal of Behavioral Medicine.

Sarah L. Szanton, from Johns Hopkins University in Baltimore, and colleagues investigated the cross-sectional association between self-reported racial discrimination and RBC oxidative stress in a biracial, socioeconomically heterogenous cohort of 629 participants (mean age, 49 years) from the Healthy Aging in Neighborhoods of Diversity across the Life Span study. Racial discrimination was self-reported, and fluorescent heme degradation products were used to measure RBC oxidative stress. Age, smoking status, obesity, and C-reactive protein were the potential confounders.

The investigators found that racial discrimination correlated significantly with RBC oxidative stress, after adjusting for age, smoking, obesity, and C-reactive protein in a multivariable regression analysis (Beta = 0.55). Stratification by race indicated that racial discrimination remained significantly associated with RBC oxidative stress for African-Americans (Beta = 0.36), but not for whites.

"These findings suggest that there may be identifiable cellular pathways by which racial discrimination amplifies cardiovascular and other age-related disease risks," the authors write.

Full Text

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95

The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95

Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.

Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.

Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events