Rapeseed Oil Rapidly Improves Hyperlipidemia

Replacing saturated dairy fat-rich diet with rapeseed oil lowers lipoprotein, triglyceride level

THURSDAY, Sept. 29 (HealthDay News) -- For hyperlipidemic individuals, replacing a diet rich in saturated dairy fat (DF) with a rapeseed oil (RO)-based diet for three weeks improves the serum lipoprotein profile, with reductions in triglyceride levels, according to a study published in the October issue of the Journal of Internal Medicine.

David Iggman, from Uppsala University in Sweden, and colleagues investigated the impact of replacing a diet rich in saturated DF with a diet including RO-based fat on lipoprotein profile, coagulation factors, and insulin sensitivity in 20 hyperlipidemic individuals. In a crossover study, isocaloric test diets, either DF- or RO-based, were given over two three-week periods. Insulin sensitivity, blood lipoprotein profile, coagulation, and fibrinolytic factors were analyzed before and after the dietary intervention.

The investigators found changes in serum fatty acids indicative of high compliance. The RO but not DF diet correlated with reduction in levels of the following from baseline: serum cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol, cholesterol/high-density lipoprotein (HDL) cholesterol ratio, apolipoprotein (apo) B/apo A-I ratio, and factor VII coagulant activity (FVIIc). These reductions were significantly different between the diets, with the exception of the reductions in FVIIc. The RO but not the DF diet showed a modest increase in serum lipoprotein, and a trend toward increased glucose disappearance rate. The HDL cholesterol, insulin sensitivity, fibrinogen, and tissue plasminogen activator inhibitor-1 levels did not differ between diets nor change from baseline.

"Replacing DF with RO causes marked improvement of serum lipoprotein profile, including lowering of LDL cholesterol and triglycerides after only three weeks," the authors write.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95


The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95


Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.


Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.


Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events