View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
THURSDAY, Sept. 29 (HealthDay News) -- Hypofractionated intensity modulated radiotherapy (IMRT) and conventional IMRT therapy are equally effective in decreasing recurrence of intermediate- to high-risk prostate cancer at five years, according to a study presented at the anual meeting of the American Society for Radiation Oncology, held from Oct. 2 to 6 in Miami Beach.
Alan Pollack, M.D., from the University of Miami Miller School of Medicine, and colleagues compared the effectiveness of hypofractionated IMRT (given in a shorter period of time with higher doses per day), versus conventionally fractionated IMRT, in decreasing recurrence of intermediate- to high-risk prostate cancer in 303 men. Participants randomly received either hypofractionated IMRT or conventionally fractionated IMRT between 2002 and 2006. In addition, the high-risk patients received a form of hormone therapy for two years. Patients were followed up for over five years.
The investigators found that the tumor control rates were similar between the two groups with better outcomes than anticipated in the conventionally fractioned group. The hypofractionation group showed results comparable to conventionally fractionated group in two and a half fewer weeks of treatment. Both groups had relatively few side effects, with identical frequency of unsatisfactory erections and long-term rates of bowel or rectal reactions. However, patients in the conventionally fractionated group showed significantly higher bladder control.
"Hypofractionated radiation that shortens treatment by about two and a half weeks is a practical approach to effectively controlling prostate cancer, as compared to the more standard treatment for men with intermediate- to high-risk prostate cancer," the authors write.
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top