High Yield of Viral Diagnoses for RT-PCR in Respiratory Infection

But, rapid communication of RT-PCR results to clinicians has no benefit on patient care

TUESDAY, Oct. 11 (HealthDay News) -- Real-time polymerase chain reaction (RT-PCR) testing has a high yield of viral diagnoses, but rapid communication of results to clinicians has no positive impact on hospital admissions, length of hospital stay, or duration of antibiotic use for children with acute respiratory infections (ARI), according to a study published online Oct. 10 in Pediatrics.

Jérôme O. Wishaupt, M.D., from the Reinier de Graaf Hospital in Delft, Netherlands, and colleagues investigated the diagnostic yield of RT-PCR assays in 583 children (age <12 years) with suspected ARIs, and evaluated the effect of rapid communication of results to physicians on patient care. Nasal wash specimens from all patients were collected and, in addition to the standard hospital protocol, RT-PCR assays for 17 pathogens were carried out. RT-PCR results were communicated to the clinicians within 12 to 36 hours and after four weeks for patients in the intervention and control groups, respectively.

The investigators found that 82 percent of the nasal wash specimens tested positive for one or more pathogen, with respiratory syncytial virus most frequently seen (55 percent). The intervention and control groups did not differ significantly with respect to hospital admissions, length of hospital stay, or duration of antibiotic use in cases of antibiotic treatment.

"The introduction of RT-PCR testing into general clinical practice yields many viral diagnoses but does not have a significant influence on patient care," the authors write.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Debunking Three Rape Myths
Journal of Forensic Nursing, October/December 2014
Expires: 12/31/2016 CE:2.5 $24.95


Drug updates and approvals: 2014 in review
The Nurse Practitioner, 13December 2014
Expires: 12/31/2016 CE:3 $27.95


Can Food Processing Enhance Cancer Protection?
Nutrition Today, September/October 2014
Expires: 10/31/2016 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events