Evidence Suggests Obesity Tied to Altered Iron Metabolism

Obese seem to have higher hemoglobin and ferritin concentrations, lower transferrin saturation

MONDAY, Oct. 17 (HealthDay News) -- Evidence suggests that obesity is associated with higher hemoglobin and ferritin concentrations and lower transferrin saturation, according to a review published online Oct. 9 in Obesity Reviews.

H.L. Cheng, from the University of Sydney in Australia, and colleagues reviewed the available literature to investigate the correlation between obesity and altered iron metabolism. A total of 25 studies meeting the eligibility criteria were included, which recruited participants aged 18 years and older and with a body mass index of 30 kg/m² or more. Iron status in free-living obese individuals was assessed in 10 of the studies, and 15 evaluated baseline biomarkers from bariatric surgery candidates.

The investigators identified 10 studies which used a nonobese comparison group. In these, higher mean hemoglobin concentrations were seen in seven obese groups, significantly higher ferritin levels in six groups, and significantly lower transferrin saturation in four obese groups. There was insufficient evidence to draw conclusions regarding the mean differences seen for soluble transferrin receptor, hepcidin, or C-reactive protein.

"The obese tended to have higher hemoglobin and ferritin concentrations and lower transferrin saturation compared to the nonobese," the authors write. "This systematic review supports evidence for obesity-associated disturbances in iron metabolism, the mechanisms for which are currently undefined."

The study was supported by Meat and Livestock Australia.

Full Text (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95

The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95

Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.

Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.

Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events