New Estimates of Rotavirus-Attributable Diarrhea Mortality

In 2008, there were 453,000 deaths worldwide in children under 5 years; most in five countries

TUESDAY, Oct. 25 (HealthDay News) -- Worldwide in 2008, 453,000 deaths in children younger than 5 years old resulted from diarrhea attributable to rotavirus, according to a meta-analysis published online Oct. 25 in The Lancet Infectious Diseases.

Jacqueline E. Tate, Ph.D., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues reviewed available literature to estimate the worldwide rotavirus-related deaths in children younger than 5 years in 2008, before the introduction of a universal rotavirus vaccination program. Studies with at least 100 children younger than age 5 who were hospitalized with diarrhea were included. Data from countries that participated in the World Health Organization-coordinated Global Rotavirus Surveillance Network and met the study criteria were also analyzed. The studies were classified into five categories on the basis of region, and the level of child mortality where the study was conducted. Rotavirus-associated mortality in each group was estimated, and regional mortality estimates were added to derive a worldwide estimate.

The investigators found that, worldwide in 2008, 453,000 deaths were attributable to rotavirus-induced diarrhea in children younger than 5 years. These accounted for 37 percent of diarrhea-attributed deaths and 5 percent of all deaths in children younger than 5 years. The Democratic Republic of the Congo, Ethiopia, India, Nigeria, and Pakistan accounted for more than half of all deaths attributable to rotavirus infection, with India alone accounting for 22 percent of deaths.

"Our new estimates can be used to advocate for rotavirus vaccine introduction and to monitor the effect of vaccination on mortality once introduced," the authors write.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.

Powered by

Featured Jobs



Benefits of Membership

FREE E-Newsletters
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues

CESaver
Join our CESaver program to earn up to 100 contact hours for only $34.95
Register Now

Lippincott's NursingCenter.com
Explore a world of online resources

Become a Member