CDC to Discontinue Provision of Botulinum Toxoid Vaccine

Decision applies to workers in occupational risk of exposure

THURSDAY, Oct. 27 (HealthDay News) -- The U.S. Centers for Disease Control and Prevention will stop providing botulinum toxoid (PBT) for the vaccination of people whose occupations put them at risk for exposure to botulinum serotypes A, B, C, D, and E, according to a report published in the Oct. 28 issue of the CDC's Morbidity and Mortality Weekly Report.

Under a New Investigational Drug (IND) application, PBT has been available through the CDC since 1965 for non-research use in those whose work may put them in contact with botulinum toxin or neurotoxin-producing species of Clostridium.

The decision to discontinue offering the investigational vaccine was based on current data suggesting a decline in immunogenicity of some toxin serotypes, possibly related to the fact that the available vaccine was manufactured more than 30 years ago. Furthermore, the incidence of moderate local reactions to annual booster doses, first noted about 20 years ago, has been increasing.

According to the CDC, "on average, approximately 200 to 300 persons received PBT annually during 2008 to 2010 under the CDC-sponsored IND for PBT. To allow recent vaccinees to complete the primary series, the IND will remain in effect through May 31, 2012."

Full Text

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Blunt Chest Trauma
Journal of Trauma Nursing, November/December 2014
Expires: 12/31/2016 CE:2 $21.95

The School Age Child with Congenital Heart Disease
MCN, The American Journal of Maternal/Child Nursing, January/February 2015
Expires: 2/28/2017 CE:2.5 $24.95

Understanding multiple myeloma
Nursing Made Incredibly Easy!, January/February 2015
Expires: 2/28/2017 CE:2 $21.95

More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles

Comprehensive Care: Looking Beyond the Presenting Problem
Journal of Christian Nursing, January/March 2015
Free access will expire on March 2, 2015.

Pain and Alzheimer dementia: A largely unrecognized problem
Nursing Made Incredibly Easy!, January/February 2015
Free access will expire on February 16, 2015.

Glycemic control in hospitalized patients
Nursing2015 Critical Care, January 2015
Free access will expire on February 16, 2015.

More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events