Overactive Bladder Prevalent in Patients With Diabetes

Seen in 22.5 percent of patients with diabetes; increased prevalence with age, diabetes duration

THURSDAY, Nov. 10 (HealthDay News) -- Overactive bladder (OAB) is prevalent in patients with type 2 diabetes, with the prevalence higher in older patients and those with long-standing diabetes, according to a study published in the November issue of Urology.

Rue-Tsuan Liu, M.D., from the Chang Gung University College of Medicine in Kaohsiung, Taiwan, and colleagues evaluated OAB with and without incontinence (OAB wet and dry), and investigated associated risk factors of OAB wet in 1,359 patients with type 2 diabetes. All patients completed a self-administered questionnaire containing the OAB symptom score (OABSS). The association between OAB and OAB wet risk and age, gender, diabetes duration, waist circumference, glycated hemoglobin, high-sensitivity C-reactive protein, and diabetes-associated complications was assessed.

The investigators found that 22.5 percent of the patients had OAB, with 11.7 and 10.8 percent of patients reporting OAB dry and OAB wet, respectively. The differences in symptom severity between patients without OAB, and those with OAB dry and OAB wet were statistically significant (OABSS 2.5 ± 1.4, 5.9 ± 1.6, and 8.9 ± 2.6, respectively). Patients older than 50 years with diabetes duration of more than 10 years, had a 2.4- and 4.2-fold greater prevalence of OAB and OAB wet, respectively. On multivariate analysis, independent risk factors of OAB and OAB wet were age and male gender, and age and waist circumference, respectively. For patients with and without OAB, glycated hemoglobin and high-sensitivity C-reactive protein levels were similar.

"The results from the present study have demonstrated a high prevalence (22.5 percent) of OAB in patients with type 2 diabetes mellitus," the authors write.

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