Leg Motor Restlessness More Common in Parkinson's

LMR, but not restless leg syndrome is significantly more likely in early unmedicated Parkinson's

THURSDAY, Nov. 10 (HealthDay News) -- Patients with early, unmedicated Parkinson's disease (PD) have a significantly increased risk for leg motor restlessness (LMR), but not restless legs syndrome (RLS), according to a study published online Nov. 9 in Neurology.

Michaela D. Gjerstad, Ph.D., from the Stavanger University Hospital in Norway, and colleagues compared the risk and correlates of leg restlessness in 200 drug-naive patients with early, unmedicated PD and 173 age- and gender-matched controls. Structured interviews, clinical examinations, and blood samples were used for assessment. All participants were Caucasian.

The investigators found that leg restlessness was reported in 40.5 percent of patients and 17.9 percent of controls, of which 15.5 percent of patients and 9.2 percent of controls met the criteria for RLS. After exclusion of potential RLS mimics and individuals with LMR, 12.5 percent of patients and 6.9 percent of controls remained. The relative risk for RLS was 1.76 (P = 0.089), and of LMR was 2.84 (P = 0.001) in PD. Patients with RLS had more sleep disturbances, and those with RLS and LMR had increased Montgomery and Åsberg Depression Rating Scale scores. There were no other major differences seen in motor or cognitive function, or in relevant blood tests for patients with PD, with or without RLS or LMR.

"LMR and not RLS occurs with a near three-fold higher risk as compared to controls in early PD," the authors write.

One of the study authors disclosed financial ties to the pharmaceutical industry.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Copyright © 2011 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

Meeting the Needs of Family Members of ICU Patients
Critical Care Nursing Quarterly, October/December 2014
Free access will expire on December 22, 2014.


Dealing with the specter of phantom limb pain
Nursing2014 , November 2014
Free access will expire on December 8, 2014.


The Power of Nursing Peer Review
JONA: Journal of Nursing Administration, November 2014
Free access will expire on December 8, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events