No Rise in Intussusception After Rotavirus Shot Revival

No increase seen in intussusception discharges since 2006 reintroduction of rotavirus vaccine

TUESDAY, Jan. 10 (HealthDay News) -- The reintroduction of the rotavirus vaccination in the United States has not resulted in an increase in the rate of infant hospital discharges for intussusception, according to a study published online Jan. 2 in the Archives of Pediatrics & Adolescent Medicine.

Joseph S. Zickafoose, M.D., from the University of Michigan in Ann Arbor, and colleagues investigated whether hospital discharges for intussusception have changed since the reintroduction of rotavirus vaccine in the United States. Participants included children younger than 1 year, with a discharge diagnosis of intussusception, who were identified from nationally representative data sets of pediatric hospital discharges in the United States for four years prior to the vaccine reintroduction (1997, 2000, 2003, and 2006) and one year after vaccine reintroduction (2009).

The investigators found that, from 1997 to 2006, there was a small decrease in the rate of intussusception discharges (41.6 to 36.5 per 100,000 infants), with no change in the total number of discharges. The predicted rate of hospital discharges for intussusception for 2009 was 36.0 per 100,000 infants, and the measured rate was 33.3 per 100,000 infants.

"The reintroduction of rotavirus vaccine since 2006 has not resulted in a detectable increase in the number of hospital discharges for intussusception among U.S. infants," the authors write.

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