Sleep Disturbance Linked to Cardiometabolic Disease Risk

Disturbed sleep tied to elevated risk of obesity, diabetes, stroke, MI, coronary artery disease

MONDAY, Jan. 23 (HealthDay News) -- Sleep duration and sleep disturbance are associated with cardiometabolic disease, according to a study published online Dec. 12 in the Journal of Sleep Research.

Michael A. Grandner, Ph.D., from the University of Pennsylvania in Philadelphia, and colleagues analyzed data on 138,201 adult participants (mean age, 48.8 years) from the 2006 Behavioral Risk Factor Surveillance System to assess the association of self-reported sleep symptoms with cardiometabolic health issues (myocardial infarction, stroke, coronary artery disease, diabetes, and obesity).

After adjusting for demographic, socioeconomic, and health risk factors, the researchers found that sleep duration correlated significantly with obesity (odds ratio [OR], 1.18), diabetes (OR, 1.18), myocardial infarction (OR, 1.36), stroke (OR, 1.22), and coronary artery disease (OR, 1.59). A significant association remained for obesity (OR, 1.14), myocardial infarction (OR, 1.23), and coronary artery disease (OR, 1.43) after fully adjusting for variables that included physical health. Sleep disturbance (difficulty falling asleep, staying asleep, and sleeping too much) was a significant risk factor for obesity, myocardial infarction, stroke, coronary artery disease, and diabetes; and following adjustment, the effects for obesity, myocardial infarction, and coronary artery disease were the most robust.

"These data suggest that sleep disturbance may be an important indicator of cardiometabolic disease risk. Future studies are needed to evaluate the temporal relationships among these measures and whether sleep intervention could reduce cardiometabolic consequences," the authors write.

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