COPD Assessment Test Predicts Exacerbation Severity

Baseline scores elevated in frequent exacerbators and scores increase at exacerbation

FRIDAY, Jan. 27 (HealthDay News) -- The COPD Assessment Test (CAT) provides a reliable score of exacerbation severity in patients with chronic obstructive pulmonary disease (COPD), according to a study published online Jan. 26 in the American Journal of Respiratory and Critical Care Medicine.

Alex J. Mackay, of the University College London Medical School, and colleagues followed 161 patients enrolled in the London COPD cohort. The patients completed the CAT at baseline while in a stable state, at exacerbation, and during recovery. Frequent exacerbators were defined as two or more exacerbations per year.

The researchers found that frequent exacerbators had significantly higher baseline CAT scores than infrequent exacerbators (19.5 ± 6.6 versus 16.8 ± 8.0). In 152 exacerbations, CAT scores rose significantly, from an average baseline value of 19.4 ± 6.8 to 24.1 ± 7.3 at exacerbation. Change in CAT score from baseline to exacerbation onset was significantly but weakly related to change in serum C-reactive protein, but not to change in fibrinogen. At exacerbation, rises in CAT score were significantly related to falls in forced expiratory volume in one second. Median recovery time, as judged by symptom diary cards, was significantly associated with the time taken for the CAT score to return to baseline.

"The CAT provides a reliable score of exacerbation severity, and its incorporation into assessment strategies may aid health care professionals to determine the severity of exacerbations and potentially assist management," the authors write.

The study was funded by GlaxoSmithKline.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

Dogs as Pets, Visitors, Therapists and Assistants
Home Healthcare Nurse, November/December 2014
Free access will expire on January 5, 2015.


Tracheostomy Care
Nursing2014 Critical Care, November 2014
Free access will expire on December 22, 2014.


Effective management of ARDS
The Nurse Practitioner, 13December 2014
Free access will expire on December 22, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events