Disc Degeneration More Likely in Overweight, Obese Adults

Higher body mass index linked to greater severity in lumbar degenerative disc disease

MONDAY, Jan. 30 (HealthDay News) -- Overweight and obese adults are significantly more likely to have lumbar disc degeneration compared with those who have a normal body mass index (BMI), according to a study published online Jan. 27 in Arthritis & Rheumatism.

Dino Samartzis, D.Sc., from the University of Hong Kong, and colleagues conducted a cross-sectional study in which 2,599 Southern Chinese volunteers (1,040 male and 1,559 female; mean age, 41.9 years) underwent radiographic and clinical assessment, including sagittal T2-weighted magnetic resonance imaging of the lumbar spine. Asian-modified BMI (kg/m²) categories were utilized.

The researchers detected disc degeneration in 72.7 percent of the volunteers. BMI was significantly higher in subjects with disc degeneration (mean BMI, 23.3 kg/m²) compared with subjects without degeneration (mean BMI, 21.7 kg/m²). A significant increase in the number of degenerated levels, global severity of disc degeneration, and end-stage disc degeneration with disc space narrowing was observed in patients with elevated BMI. Compared with normal-weight individuals, there was a positive linear trend between BMI categories and the overall presence of disc degeneration (overweight odds ratio [OR], 1.30; 95 percent confidence interval [CI], 1.03 to 1.62; obese OR, 1.79; 95 percent CI, 1.17 to 2.74). End-stage disc degeneration with disc space narrowing was significantly more likely in obese individuals (OR, 1.72; 95 percent CI, 1.23 to 2.41).

"In one of the largest studies to systematically assess lumbar disc degeneration on MRI, our study noted a significant association between the presence, increased extent, and global severity of disc degeneration in overweight and obese adults," the authors write.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

Featured Jobs



Benefits of Membership

FREE E-Newsletters
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues

CESaver
Join our CESaver program to earn up to 100 contact hours for only $34.95
Register Now

Lippincott's NursingCenter.com
Explore a world of online resources

Become a Member