View Entire Collection
By Clinical Topic
Diabetes – Summer 2012
Future of Nursing Initiative
Heart Failure - Fall 2011
Influenza - Winter 2011
Nursing Ethics - Fall 2011
Trauma - Fall 2010
Traumatic Brain Injury - Fall 2010
Fluids & Electrolytes
WEDNESDAY, Feb. 1 (HealthDay News) -- Repeated screening by flexible sigmoidoscopy (FSG) increases the detection of colorectal cancer or advanced adenoma in women and men, according to a study published online Jan. 31 in the Journal of the National Cancer Institute.
Joel L. Weissfeld, M.D., M.P.H., of the University of Pittsburgh Cancer Institute, and colleagues reported outcomes from participants of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial who were randomly assigned to receive FSG. Patients were screened by 60-cm FSG at study entry and three or five years later. Results from subsequent diagnostic intervention were recorded and outcomes were compared based on gender and age.
The researchers found that, of 77,447 enrollees, 86.6 percent had at least one FSG and 50.9 percent had two FSGs. Diagnostic intervention occurred in 74.9 and 78.7 percent of patients after a positive first or repeat FSG, respectively. The screening yield increased by 32 percent based on the second FSG. After the first screening, colorectal cancer or advanced adenoma was detected in 37.8 per 1,000 persons, and after all screenings, in 49.8 per 1,000 persons. The yield of cancer or advanced adenoma was increased by the second FSG by 26 percent in women and by 34 percent in men. Of 223 subjects who received a diagnosis of colorectal carcinoma within one year of a positive FSG, stage I and II disease were seen in 64.6 and 17.5 percent, respectively.
"Repeat FSG increased the detection of colorectal cancer or advanced adenoma in women by one-fourth and in men by one-third," the authors write.
Full Text (subscription or payment may be required)
Sign up for our free enewsletters to stay up-to-date in your area of practice - or take a look at an archive of prior issues
Join our CESaver program to earn up to 100 contact hours for only $34.95
Explore a world of online resources
Back to Top