Repeat Flexible Sigmoidoscopy Increases Detection of CRC

Rescreening increases yield of colorectal cancer or advanced adenomas by 32 percent

WEDNESDAY, Feb. 1 (HealthDay News) -- Repeated screening by flexible sigmoidoscopy (FSG) increases the detection of colorectal cancer or advanced adenoma in women and men, according to a study published online Jan. 31 in the Journal of the National Cancer Institute.

Joel L. Weissfeld, M.D., M.P.H., of the University of Pittsburgh Cancer Institute, and colleagues reported outcomes from participants of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial who were randomly assigned to receive FSG. Patients were screened by 60-cm FSG at study entry and three or five years later. Results from subsequent diagnostic intervention were recorded and outcomes were compared based on gender and age.

The researchers found that, of 77,447 enrollees, 86.6 percent had at least one FSG and 50.9 percent had two FSGs. Diagnostic intervention occurred in 74.9 and 78.7 percent of patients after a positive first or repeat FSG, respectively. The screening yield increased by 32 percent based on the second FSG. After the first screening, colorectal cancer or advanced adenoma was detected in 37.8 per 1,000 persons, and after all screenings, in 49.8 per 1,000 persons. The yield of cancer or advanced adenoma was increased by the second FSG by 26 percent in women and by 34 percent in men. Of 223 subjects who received a diagnosis of colorectal carcinoma within one year of a positive FSG, stage I and II disease were seen in 64.6 and 17.5 percent, respectively.

"Repeat FSG increased the detection of colorectal cancer or advanced adenoma in women by one-fourth and in men by one-third," the authors write.

Abstract
Full Text (subscription or payment may be required)
Editorial

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Debunking Three Rape Myths
Journal of Forensic Nursing, October/December 2014
Expires: 12/31/2016 CE:2.5 $24.95


Drug updates and approvals: 2014 in review
The Nurse Practitioner, 13December 2014
Expires: 12/31/2016 CE:3 $27.95


Can Food Processing Enhance Cancer Protection?
Nutrition Today, September/October 2014
Expires: 10/31/2016 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events