Occasional Hard Drug Use in Mid-Life Hikes Mortality Risks

Trajectory analysis shows significantly increased risk for early frequent/later occasional users

THURSDAY, Feb. 2 (HealthDay News) -- The occasional use of hard drugs in middle age is linked to significantly increased risk of all-cause mortality, according to a study published online Jan. 25 in the Journal of General Internal Medicine.

Stefan G. Kertesz, M.D., of the Birmingham VA Medical Center in Alabama, and associates described trajectories of cocaine, amphetamines, and opiate use among adults in community settings, and their association with all-cause mortality. A cohort of 4,301 adults was assessed for drug use from 1987-88 to 2005-06.

The researchers identified four trajectories: nonusers, early occasional users, persistent occasional users, and early frequent/later occasional users. These trajectories correlated with anticipated patterns of demographics, other substance use, education, and family background. Early frequent/later occasional users had significantly increased all-cause mortality (hazard ratio, 4.94; P = 0.006), after adjusting for demographics, baseline health status, health behaviors, and psychosocial characteristics.

"The positive association found between drug use and all-cause mortality is not likely one of direct cause and effect," the authors write. "We speculate that continuing adult drug use signifies complex patterns of vulnerability or behavior that contribute to mortality in ways not captured by our models."

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

Abdominal Pain: An Approach to a Challenging Diagnosis
AACN Advanced Critical Care, July/September 2014
Free access will expire on October 13, 2014.


HIPAA Compliance Practice Tips
Professional Case Management, July/August 2014
Free access will expire on September 29, 2014.


Follow the leader: How does “followership” influence nurse burnout?
Nursing Management, August 2014
Free access will expire on September 29, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events