Women With MI More Likely to Present Without Chest Pain

Gender difference also seen for in-hospital mortality rates; attenuated with increasing age

TUESDAY, Feb. 21 (HealthDay News) -- Women suffering a myocardial infarction (MI) are more likely than men of the same age to present without chest pain and have higher in-hospital mortality, according to a study published in the Feb. 22 issue of the Journal of the American Medical Association.

To investigate the association between gender, symptom presentation, and hospital mortality, John G. Canto, M.D., M.S.P.H., from the Watson Clinic and Lakeland Regional Medical Center in Florida, and colleagues conducted an observational study of 1,143,513 registry patients (481,581 women) from the National Registry of Myocardial Infarction, 1994 to 2006.

The researchers found that significantly more female than male patients presented without chest pain (42.0 versus 30.7 percent). Sex-specific differences in MI presentation without chest pain declined with advancing age (age-specific multivariable adjusted odds ratios [ORs] for women compared to men: younger than 45 years, 1.30; 45 to 54 years, 1.26; 55 to 64 years, 1.24; 65 to 74 years, 1.13; and 75 years or older, 1.03). The in-hospital mortality rate was 14.6 percent for women and 10.3 percent for men. Greater hospital mortality was seen for younger women than younger men, presenting without chest pain, with the differences decreasing and then reversing with advancing age (adjusted ORs for age younger than 45 years, 1.18; 45 to 54 years, 1.13; 55 to 64 years, 1.02; 65 to 74 years, 0.91; and 75 years or older, 0.81).

"Sex differences in clinical presentation without chest pain and in mortality were attenuated with increasing age," the authors write.

Several authors disclosed financial ties to pharmaceutical and medical device companies. The National Registry of Myocardial Infarction was funded by Genentech.

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles

Debunking Three Rape Myths
Journal of Forensic Nursing, October/December 2014
Expires: 12/31/2016 CE:2.5 $24.95


Drug updates and approvals: 2014 in review
The Nurse Practitioner, 13December 2014
Expires: 12/31/2016 CE:3 $27.95


Can Food Processing Enhance Cancer Protection?
Nutrition Today, September/October 2014
Expires: 10/31/2016 CE:2 $21.95


More CE Articles

Subscribe to Recommended CE

Recommended Nursing Articles Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events