Approximately 30 percent increase in complications with each higher chronic kidney disease stage
FRIDAY, March 2 (HealthDay News) -- Higher rates of bariatric surgery complications are seen in patients with chronic kidney disease (CKD), with advancing disease stage correlating with increasing complication rates, according to research published online March 1 in the Journal of the American Society of Nephrology.
Nicole A. Turgeon, M.D., of Emory University in Atlanta, and colleagues analyzed data from 27,736 bariatric surgery patients to assess the effect of CKD on the risks of bariatric surgery.
The researchers found that 0.12 percent of patients were undergoing long-term dialysis before surgery. Of those patients not undergoing dialysis, 75.0 percent either had normal estimated glomerular filtration rate (GFR) or stage 1 CKD, and 18.07, 6.25, 0.34, and 0.33 percent had stage 2, 3, 4, and 5 CKD, respectively. CKD stage was associated with complication rate in an unadjusted analysis, from 4.6 percent for those with normal estimated GFR or stage 1 CKD to 9.9 percent for those with stage 5 CKD. On multivariable analysis, CKD stage predicted increased complication rates, with an odds ratio of 1.30 for each higher CKD stage. Despite the higher risk, the overall rate of complications was less than 10 percent.
"In conclusion, this study demonstrates that patients with higher stages of CKD undergoing bariatric surgery had higher complication rates than patients with lower stages of CKD or with normal renal function. Although the relative risk is higher, the absolute risk for complications after bariatric surgery remains low in this patient population," the authors write.
Full Text (subscription or payment may be required)