Cardiovascular Event Risk Not Up for Living Kidney Donors

No increased risk of death or major cardiovascular event in first 10 years post-transplant

FRIDAY, March 2 (HealthDay News) -- For living kidney donors, there is no increase in the risk of major cardiovascular events or death in the first decade following donation, compared with a representative sample of the healthiest segment of the general population, according to a study published online March 1 in BMJ.

To investigate whether people who donate a kidney have an increased risk of cardiovascular disease, Amit X. Garg, M.D., Ph.D., of the University of Western Ontario in London, Canada, and colleagues reviewed data from 2,028 living kidney donors (median age at time of donation, 43 years) and 20,280 matched controls, selected from the healthiest segment of the general population.

The researchers found that, over a median of 6.5 years of follow-up, the risk of a composite outcome of death or a first major cardiovascular event was lower in donors than in non-donors (2.8 versus 4.1 events per 1,000 person years; hazard ratio [HR], 0.66). There was no difference for donors versus non-donors for the risk of major cardiovascular events not causing death (1.7 versus 2.0 events per 1,000 person years; HR, 0.85; 95 percent confidence interval, 0.57 to 1.27). When each group was analyzed separately, advanced age and lower income correlated with an increased risk of death and major cardiovascular events in both groups.

"The risk of major cardiovascular events in donors is no higher in the first decade after kidney donation compared with a similarly healthy segment of the general population," the authors write.

Full Text
Editorial (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

Meeting the Needs of Family Members of ICU Patients
Critical Care Nursing Quarterly, October/December 2014
Free access will expire on December 22, 2014.


Dealing with the specter of phantom limb pain
Nursing2014 , November 2014
Free access will expire on December 8, 2014.


The Power of Nursing Peer Review
JONA: Journal of Nursing Administration, November 2014
Free access will expire on December 8, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events