Low Blood Adiponectin Predicts Future Asthma Risk in Women

Women with levels in lowest tertile at year 15 have about two-fold increased asthma risk at year 20

FRIDAY, April 6 (HealthDay News) -- Middle-aged women with low blood adiponectin levels are about twice as likely to develop asthma, particularly if they smoke, according to a study published online April 6 in the American Journal of Respiratory and Critical Care Medicine.

Noting that their previous study found a link between low serum adiponectin and incident asthma in women but did not address whether low adiponectin predicted future asthma or if asthma lowered adiponectin levels, Akshay Sood, M.D., M.P.H., from the University of New Mexico in Albuquerque, and colleagues analyzed incident asthma and serum adiponectin levels in 1,450 women (1,011 premenopausal). The participants were from the Coronary Artery Risk Development in Young Adults cohort who were examined at 10, 15, and 20 years.

The researchers found that, after multivariable adjustment, women whose adiponectin levels were in the lowest third (<7 mg/L) at year 15 had a significantly higher risk of incident asthma at year 20 (odds ratio, 2.07), particularly if they currently smoked. Low adiponectin levels were more predictive than body mass index. In contrast, prevalent asthma at year 10 did not predict adiponectin levels at year 15.

"Serum adiponectin affects future risk for asthma in women and not vice versa," Sood and colleagues conclude. "Measures that raise systemic adiponectin concentrations may lead to newer ways to prevent asthma among women, particularly among those who smoke."

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Powered by

jQuery UI Accordion - Default functionality

For life-long learning and continuing professional development, come to Lippincott's NursingCenter.

Nursing Jobs Plus
Featured Jobs
Recommended CE Articles Recommended Nursing Articles

What internal motivators drive RNs to pursue a BSN?
Nursing2014 , October 2014
Free access will expire on November 24, 2014.


Breast Cancer Risk Assessment in Primary Care
MCN, The American Journal of Maternal/Child Nursing, September/October 2014
Free access will expire on November 10, 2014.


Nurses spurring innovation
Nursing Management, October 2014
Free access will expire on November 10, 2014.


More Recommended Articles

Subscribe to Recommended Articles

Evidence Based Practice Skin Care Network NursingCenter Quick Links What’s Trending Events